Halda Therapeutics is a New Haven CT based venture-backed biotechnology company focused on the development of a novel heterobifunctional small molecule platform technology as an anti-cancer therapeutic modality. Halda was founded in 2019 by Professor Craig Crews (Yale University) and is funded by top-tier venture capital firms, raising $51M for a Series B round in December 2021.

We are looking for a biology team leader with a strong foundation in cancer cell biology/translational biology to contribute to and drive strategy for preclinical oncology drug discovery programs. The candidate should have a background in small molecule drug discovery, including a minimum of 5 years in industry as a part of drug development programs. An ideal candidate would also bring to the role 2+ years of program leadership and personnel management experience.

The successful candidate would be expected to manage and mentor team members. They would guide team leads to define and execute on short-term and long-term project goals through a combination of in vitro and in vivostudies to advance lead compounds while developing an understanding of the underlying biology and mechanism of action. The candidate would also be expected to contribute to the development of the technology platform, through a combination of benchwork, data organization, and presentation for the scientific and management teams.

Requirements include:

• Ph.D. in cell biology/biochemistry/genetics or a related field, and a minimum of 5 years of pharma/biotech experience in drug development.
• Experience managing direct reports and mentoring professional growth
• Prior experience leading preclinical discovery projects, including designing, developing, and overseeing cell-based assays and in vivo studies.
• First-hand experience engineering cell lines to overexpress, mutate, knock down, and knock out genes of interest, and standard analytical techniques such as immunoblotting, qPCR, ELISA, flow cytometry etc.
• Experience designing in vivo studies and understanding of PK/PD and PD/efficacy relationships.
• Ability to provide translational guidance, including formulating therapeutic hypotheses for well-defined patient populations in oncology.
• Ability to stay on top of the latest scientific research in the targeted therapy field, with a commitment to deep knowledge in project-specific biology, from target validation to clinical data.
• Ability to identify and manage relationships with KOLs and external advisors to aid in advancement of programs to IND filing.
• Ability to address specific questions though experimental design and the ability to interpret and communicate results to the scientific team while advancing aggressive program timelines.
• Ability to proactively identify, evaluate, and manage external vendors of assay services.

An ideal candidate will also have:

• Prior 2+ year drug discovery program leadership experience in an industry setting.
• Excellent interpersonal, communication, organizational, teamwork, and planning skills to accomplish multiple tasks and meet deadlines in a timely manner.
• Ability to function within a multi-disciplinary discovery and development team to advance small-molecule drug discovery projects.

Job Type: Full-time

COVID-19 considerations:
Our labs are open at Halda Therapeutics, and all of the appropriate safety protocols from the State of CT and CDC are being implemented. Compliance with Mandatory Vaccination Policy required.

Job Type: Full-time

Pay: $161,844.00 - $224,974.00 per year

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Flexible spending account
• Health insurance
• Health savings account
• Paid time off
• Parental leave
• Tuition reimbursement
• Vision insurance

Schedule:

• Monday to Friday

Supplemental pay types:

• Bonus pay

COVID-19 considerations:
Our labs and offices are fully open. We have implemented all of the appropriate safety protocols from the State of CT and CDC to keep our employees safe, including face coverings (as mandated by the City of New Haven) and a Mandatory Vaccination Policy.

Work Location: One location

Please Note :
www.epokagency.com is the go-to platform for job seekers looking for the best job postings from around the web. With a focus on quality, the platform guarantees that all job postings are from reliable sources and are up-to-date. It also offers a variety of tools to help users find the perfect job for them, such as searching by location and filtering by industry. Furthermore, www.epokagency.com provides helpful resources like resume tips and career advice to give job seekers an edge in their search. With its commitment to quality and user-friendliness, Site.com is the ideal place to find your next job.