Why Seres Therapeutics

Seres Therapeutics is a commercial-stage company developing novel microbiome therapeutics for serious diseases. Our lead program, VOWST™, obtained U.S. FDA approval in April 2023 as the first orally administered microbiota-based therapeutic to prevent recurrence of C. difficile infection (CDI) in adults following antibacterial treatment for recurrent CDI and is being commercialized in collaboration with Nestlé Health Science. We are evaluating SER-155 in a Phase 1b study in patients receiving allogeneic hematopoietic stem cell transplantation to reduce incidences of gastrointestinal infections, bloodstream infections, and graft-versus-host disease as well as additional preclinical stage programs targeting Infection Protection in medically compromised patients. We are also conducting research to inform further development of microbiome therapeutics for ulcerative colitis.

Position Summary

At Seres, we're leading the microbiome revolution — and our most revolutionary asset is our team. Their courage and deep commitment are what drives us on our mission to transform the lives of patients worldwide with revolutionary microbiome therapeutics.

Seres has developed a suite of proprietary analytical techniques spanning microbiology, molecular biology, and chemistry. You will be playing a key role in designing and implementing the studies necessary to refine and transfer methods developed in Analytical Development to Quality Control or external vendors. Your scientific expertise will be applied to challenging problems associated with characterizing and releasing therapeutics comprised of consortia of live bacteria.

What You'll Do

• Closely monitor assay performance to rapidly identify and remediate assay weaknesses prior to assay transfer into Quality Control.
• Lead assay investigations and troubleshooting efforts as needed.
• Author test methods and qualify methods under appropriate ICH or FDA guidelines.
• Conduct lab work as part of protocol executions.
• Work directly with Quality Control or external vendors to support assay and technology transfer efforts.
• Author and review study protocols.
• Author and review technical reports describing experimental outcomes.
• Mentor and train junior staff to execute studies.

What You'll Bring

• For Scientist I, PhD in biology, biological engineering, chemistry, or a similar field with 0-2+ years of experience or MS with 4+ years of experience. For Scientist II, PhD in biology, biological engineering, chemistry, or a similar field with 2-5+ years of experience or MS with 5-7 years of experience. Position commensurate with experience.
• Experience with assay development, including assay verification, qualification, and/or validation under ICH and/or FDA guidelines.
• Experience executing microbiological assays (i.e. CFU, microscopy, microbiological identification) or molecular assays (qPCR, ddPCR, etc.)
• Experience with JMP, GraphPad Prism, Minitab, R or similar software.
• Must be enthusiastic, proactive, collaborative, curious, and results-oriented.

Seres is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation, or any characteristic protected under applicable law.

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